1. The tumor tissue obtained by immunohistochemistry and other methods detected by biopsy or surgery, the major histocompatibility complex class I molecules, namely MHC-I molecules, (also known as human leukocyte class I antigens, namely HLA-I molecules) are Positive;

 2. If the patient is unable to obtain tumor tissue, except for liver cancer and liver metastatic tumors, if the patient has not reached the end-stage or cachexia state, treatment may be considered. But it is strongly recommended to detect MHC-I molecules;

 3. Peripheral blood leukocytes return to the normal value or close to the normal value (>3.0×10 to the 9th power/L) (except for the normal value achieved by the use of leukocyte-enhancing drugs);

 4. Treatments without immune damage and bone marrow suppression can be used simultaneously;

 5. No severe anemia, systemic organ failure or cachexia;

 6. Liver and kidney functions are normal, and vital signs are normal;

 7. No severe allergies;

 8. If at least one of the following tumor-associated antigens is positive by serological examination or pathological examination, you can receive treatment:

 Serological detection of tumor markers (antigens) routinely carried out by clinical laboratories of hospitals related to this treatment includes: carcinoembryonic antigen (CEA), Her2/neu (c-erb b2), keratin 19 (K19, CK19, CYFRA21) -1) Antigen, Latent Membrane Protein Antigen (LMP-1), Tumor-Testicular Antigen (CT) SPANX, Sperm Protein 17 (SP17), Prostate Specific Antigen (PSA), Prostate Specific Membrane Antigen (PSMA), Milk Protein 46 antigen (BA46), alpha-fetoprotein (AFP), a melanoma antigen (MAGE-A3), prostatic acid phosphatase antigen (PAP), growth hormone antigen (Survivin), squamous cell carcinoma (SCC) antigen and There are more than 30 kinds of mucin antigen (MUC-1).

 Serological test is negative, not necessarily tumor tissue is also negative. Serological tests in some cases were negative. The tumor tissue immunohistochemical test was positive.

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