High-risk objects
        1. Patients with chronic calculous cholecystitis (the larger the stone, the higher the risk);
        2. Those who have gallbladder polyps (more than 1 cm in diameter, especially single, broad-pedicle polyps);
        3. Porcelain gallbladder or gallbladder atrophy;
        4. Patients with abnormal bile duct confluence or congenital bile duct cyst;
        5. Patients with gallbladder adenomyosis;
        6. People with chronic typhoid fever;
        7. People with primary sclerosing cholangitis;
        8. People with inflammatory bowel disease;
        9. People with diabetes.
 
Screening recommendations
        1. High-risk population: It is recommended to have serum CEA, CA199 and hepatobiliary B-ultrasound every 6 months;
        2. General population: It is recommended to take serum CEA, CA199 and hepatobiliary B-ultrasound every year, especially for women.
 
Screening recommendations
        1. High-risk population: It is recommended to have serum CEA, CA199 and hepatobiliary B-ultrasound every 6 months;
        2. General population: It is recommended to take serum CEA, CA199 and hepatobiliary B-ultrasound every year, especially for women.